Download e-book for iPad: Advances in Salivary Diagnostics by Charles F. Streckfus

By Charles F. Streckfus

ISBN-10: 3662453983

ISBN-13: 9783662453988

ISBN-10: 3662453991

ISBN-13: 9783662453995

This booklet reports the growth made in salivary diagnostics up to now 20 years and identifies the most likely path of destiny endeavors. After an introductory part describing the histological and anatomical gains of the salivary glands and salivary functionality, salivary assortment units and diagnostic systems are reviewed. the sphere of “salivaomics” is then thought of intimately, masking, for instance, proteomics, the peptidome, DNA and RNA research, biomarkers, and techniques for biomarker discovery. Salivary diagnostics for oral and systemic ailments are completely mentioned, and the function of salivary gland tissue engineering for destiny diagnostics is explored. The e-book closes through contemplating criminal matters and boundaries to salivary diagnostic improvement. Advances in Salivary Diagnostics may be an informative and stimulating reference for either practitioners and students.

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68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 78. deregulation in human breast cancer. Cancer Res. 2005;65:7065–70. Sotiriou C, Pusztai L. Gene-expression signatures in breast cancer. N Engl J Med. 2009;360:790–800. Jing F, Zhang J, Tao J, Zhou Y, Jun L, Tang X, Wang Y, Hai H. Hypermethylation of tumor suppressor genes BRCA1, p16 and 14-3-3sigma in serum of sporadic breast cancer patients. Onkologie. 2007;30:14–9. Banerjee HN, Verma M. Use of nanotechnology for the development of novel cancer biomarkers.

In stark contrast to the “invasive” process of collecting blood/ serum from patients, the noninvasive process of saliva collection is near absolute. For example, patients who are phobic to needle pricks that invariably involved for blood draws will readily accede to the friendlier procedures for saliva collection, which is largely devoid of threatening maneuvers and also compatible with a stress-free appointment. Furthermore, the fact that, unlike blood, saliva lacks clotting ability simplifies the preservation steps and makes it easier to handle.

Potential Legal Challenges to Salivary Diagnostics Fig. 2 Hierarchy of legal decision-making (Modified from Kadehjian [4] with permission from Elsevier) example, evidentiary proof ranges from “beyond a reasonable doubt” in criminal cases to “preponderance of the evidence” in civil matters or probation hearings. Lower standards of proof, such as “probable cause” and “reasonable suspicion,” are occasionally entertained. Thus, the scientific certainty of test results is subject to different levels of scrutiny depending upon the nature of legal proceedings as indicated above.

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Advances in Salivary Diagnostics by Charles F. Streckfus


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