Advances in Microbial Toxin Research and Its - download pdf or read online

By Hisashi Miyagawa, Masakazu Okada (auth.), Rajeev K. Upadhyay (eds.)

ISBN-10: 1441933840

ISBN-13: 9781441933843

ISBN-10: 1475744390

ISBN-13: 9781475744392

Microbial pollution are secondary metabolites that collect within the organism and, to a wide quantity, are metabolically inactive in the direction of the organism that produces them. the invention of penicillin, a secondary metabolite of Penicillium notatum West (= P. chrysogenum Thom), in 1929 marked a milestone within the improvement of antibiotics (microbial toxins). within the extensive reviews that this discovery, scientists chemically characterised numerous new molecules (toxins) from secondary metabolites of microbes, a few having a distinct functionality in inflicting pathogenesis in crops. pollution also are identified to playa major function in inciting animal (human) and bug illnesses and as plant progress regulators. Many universal pollution have additionally been remoted from diversified microbes displaying a large spectrum of organic task. pollution are generally divisible into a number of attribute groupings - polyketides, oxygen heterocyclic compounds, pyrons, terpenoidS, amino acids - diketopiperazines, polypeptides and so on. contemporary examine has indicated that those pollution play a huge position in plant pathogenesis, ailment epidemics, plant breeding, organic keep watch over of plant pathogens and bug pests, brought on resistance, plant-pathogen interactions and so forth. pollutants produced through weed pathogens are exploited as lead molecules in constructing environmentally pleasant herbicides.

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G. 239. 20 Walton, J. , and Panaccione, D. , 1993, Host-selective toxins and disease specificity: perspectives and progress, Annu. Rev. Phytopathol. 31 : 275. Wolpert, T. , 1989, Specific binding ofvictorin to a 100-kDa protein from oats, Proc. Natl. Acad Sci. USA 86: 4092. Wolpert, T. , 1991, Immunological comparison of the in vitro and in vivo labeled victorin binding protein from susceptible oats, Plant Physiol. 95 : 917. Wolpert, T. , 1985, Structure of v ictorin C, the major host-selective toxin from Cochliobolus victoriae, Experientia 41 : 1524.

Heredity of the disease resistance, Engeishikenjo Hokoku A (in Japanese) 12: 17. , 1994, Studies of the structure-toxicity relationship of AK-toxin, a host-specific toxin to Japanese white pear, produced by Alternaria kikuchiana : synthesis of methyl (4S, 5R)-4-(N-acetylphenylalanyl) oxy-5,6-epoxy-5-methyihex-2(E)-enoate and its stereoisomers, Chern. Pharm. Bull. 42 : 1328. , 1989, Chiral synthesis ofa key intermediate in the preparation of the AF toxin lIe, Tetrahedron Lett. 30: 6683. Levings, III, C.

Great caution must be exercised in considering the possibility of using beauvericin producing fungal strains as biological control agents of entomoparasites of plants ofeconomical interest, as it has been proposed (Wagner and Lewis, 2000). Regarding other known biological effects, it was shown that beauvericin induced strong platelet aggregation at 20 11M, which seemed to be independent from Ca2+ transport (Massini and Naf, 1980). , 1992). 86 11M. , 2000). These data suggest that beauvericin may also pose potential risks of cardiotoxicity when present as a contaminant in grains and foods.

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Advances in Microbial Toxin Research and Its Biotechnological Exploitation by Hisashi Miyagawa, Masakazu Okada (auth.), Rajeev K. Upadhyay (eds.)


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