National Research Council, Institute of Medicine, Board on's 2008 Amendments to the National Academies' Guidelines for PDF

By National Research Council, Institute of Medicine, Board on Health Sciences Policy, Division on Earth and Life Studies, Board on Life Sciences, Human Embryonic Stem Cell Research Advisory Committee

ISBN-10: 0309122201

ISBN-13: 9780309122207

ISBN-10: 030912221X

ISBN-13: 9780309122214

In 2005, the nationwide Academies published the record instructions for Human Embryonic Stem phone examine, which provided a typical set of moral criteria for a box that, end result of the absence of accomplished federal investment, was once missing nationwide criteria for research.

In order to maintain the tips modern, given the fast velocity of clinical advancements within the box of stem cellphone study, the Human Embryonic Stem phone study Advisory Committee was once demonstrated in 2006 with aid from The Ellison scientific starting place, The Greenwall origin, and the Howard Hughes clinical Institute.

As it did in 2007, the Committee pointed out matters that warranted revision, and this publication addresses these matters in a moment set of amendments. most significantly, this e-book addresses new medical advancements in reprogramming of somatic cells to pluripotency through including a brand new part and revising different proper sections of the Guidelines.

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Additional info for 2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research

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In the case of lines imported from another institution, documentation that these criteria were met at the time of derivation will suffice. 1. 3 Each institution should maintain a registry of its investigators who are conducting hES cell research and ensure that all registered users are kept up to date with changes in guidelines and regulations regarding the use of hES cells. 4 All protocols involving the combination of hES cells with nonhuman embryos, fetuses, or adult animals must be submitted to the local IACUC for review of animal welfare issues and to the ESCRO committee for consideration of the consequences of the human contributions to the resulting chimeras.

2 Reproductive Uses of NT These guidelines also do not apply to reproductive uses of nuclear transfer (NT), which are addressed in the 2002 report Scientific and Medical Aspects of Human Reproductive Cloning, in which the National Academies recommended that “Human reproductive cloning should not now be practiced. ” Although these guidelines do not specifically address human reproductive cloning, it continues to be the view of the National Academies that research aimed at the reproductive cloning of a human being should not be conducted at this time.

Appendix B Immunosuppressive—Suppressing a natural immune response. Implantation—The process in which a blastocyst implants into the uterine wall, where a placenta forms to nurture the growing fetus. Inner cell mass—The cluster of cells inside the blastocyst that give rise to the embryonic disk of the later embryo and, ultimately, the fetus. Interspecific—Between species. In utero—In the uterus. In vitro—Literally, “in glass,” in a laboratory dish or test tube; in an artificial environment. In vitro fertilization (IVF)—An assisted reproductive technique in which fertilization is accomplished outside the body.

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2008 Amendments to the National Academies' Guidelines for Human Embryonic Stem Cell Research by National Research Council, Institute of Medicine, Board on Health Sciences Policy, Division on Earth and Life Studies, Board on Life Sciences, Human Embryonic Stem Cell Research Advisory Committee


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